| Pubsearch |
|
[Search for
Articles
/
PubSources
/
Genes
/
Hits
/
Terms
/
Alleles
/
Symbols
/
Community Reference
/
Germplasms
/
Phenotypes
/
All
]
[Find Help Curation Guide / Discussion Mailing List ] |
[Add
Article /
Articles in Bulk /
Gene /
Locus /
Term /
Communication /
Allele /
Symbol /
Community Reference /
Germplasm /
User /
Community Submission
Other Annotations
Bulk Annotation Upload
]
[Browse Gene Ontology / Tair Ontology / Annotation Tasks ] [Submit SourceForge Bug Report ] |
Article Actions: [Update existing article hits / Add new hits]
| Title | ||||||
|---|---|---|---|---|---|---|
| Cytochrome P450s as reporters for circadian-regulated pathways | ||||||
| Article ID | Volume | Year | Page Start | Issue | Type | |
| 45502 | 2008 | abstract | ||||
| PubSource | TAIR Reference ID | |||||
| # 3536 19th International Conference on Arabidopsis Research | 501727711 | |||||
| Scanned Date | Scanned By | Is Local Hard | Is Downloaded | Is Scanned | ||
| Melanie Trull | ||||||
| Ref Text | Is Peer Reviewed | IsPrintRef | IsE-Ref | |||
| n | ||||||
| Link | Doi | |||||
| http://doi.org/ | ||||||
| Authors | ||||||
| *Yinghong Pan, Matthew E. Hudson, Todd P. Michael, and Mary A. Schuler | ||||||
| Abstract | ||||||
| Cytochrome P450 monooxygenases play important roles in the synthesis of diverse secondary compounds in Arabidopsis thaliana. Comparison of four datasets analyzing seedlings harvested over a two-day period of constant conditions after growth with varying photoperiods and thermocycles recorded a total of 98 P450 loci as circadian-regulated for at least one of the four conditions. Here, we further describe the circadian-regulated pathways using, as reporters, individual P450 loci that are likely to be rate-limiting in secondary metabolic pathways. RT-PCR gel blot analyses have confirmed circadian regulation of P450s in phenylpropanoid, carotenoid, oxylipin, glucosinolate and brassinosteroid biosyntheses and shown that P450 and non-P450 genes in the many branches of the phenylpropanoid pathway have similar circadian patterns of expression. In silico analyses of the subsets of co-regulated promoters have identified over-represented promoter elements in various biosynthetic pathway genes including MYB and MYB4 elements that are significantly more abundant in promoters for the core and lignin branch of phenylpropanoid metabolism. Interactions with these elements important for circadian regulation do not involve the MYB transcription factor PAP1 as previously proposed since the expression patterns of circadian-regulated P450s are the same in pap1-D mutant seedlings as in wildtype seedlings. Further analysis of circadian-regulated promoters in other biochemical pathways will provide us with the opportunity to functionally characterize novel promoter motifs that might be important in P450 circadian regulation. | ||||||
| Annotations | ||||||
Jump to page [ 1 ] |
||||||
| MedlineID | BiosisID | AgricolaID | PubMedID | PMCentralID | PubReferenceID | |
| 1699951 | ||||||
|
Related terms:
|
Related genes:
|
|||||
| comments or questions to: gmod-pubsearch-dv@lists.sourceforge.net. Bug reports can be sent to SourceForge. |